In the present study, we constructed a rat model of chronic liver failure and used FYJDHY as an intervention to observe the effect of this prescription on the expression of the connexin Gab1 (Grb2-associated binder 1) [5], TPO (thrombopoietin), and its receptor c-Mpl, the key molecule for the maintenance of hematopoietic stem cell function [6]. This evidence concerns the gene MPL and chronic liver failure.