Through KEGG pathway analysis, it was found that LPD could treat CG mainly by interfering with the pathway in Chagas diseases, cytokine-cytokine receptor interaction, measles, cancer, inflammatory bowel diseases, and hepatitis B, P13K-Akt signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, and so on. This evidence concerns the gene AKT1 and Chagas disease.