Liu et al. researched the association of dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) macrophages with clinicopathological parameters, found that DC-SIGN + macrophages were associated with immune invasive tumor-associated macrophages and indicated poor prognosis and inferior therapeutic responsiveness to fluorouracil-based adjuvant chemotherapy (Liu et al., 2020). The gene discussed is CD209; the disease is neoplasm.