Another study found that five immune-related lncRNAs containing AP001007.1, LBX-AS1, MIR155HG, MAPT-AS1, and LINC00515, regulate the tumor immune microenvironment through the interaction of cytokines and cytokine receptors, complement and coagulation cascades to affect the prognosis of glioma (Wang et al., 2020). This evidence concerns the gene MAPT and central nervous system cancer.