Thus, it was shown that the genotypes associated with an increased risk of developing T2DM, CC rs1042044, and AA rs6923761 of the GLP-1R gene polymorphism, are characterized by an increase in the plasma level of incretin in the group of obese patients with T2DM and serum glucose levels in the group of obese patients without T2DM (Skuratovskaia, 2018). This evidence concerns the gene GCG and type 2 diabetes mellitus.