KDR and Familial prostate cancer: The protein expression of VEGFRs (VEGFR-1, VEGFR-2, and VEGFR-3) was examined in human prostate epithelial PrEC cells and prostate cancer LNCaP (androgen-dependent/weakly metastatic), PC-3 (androgen-independent/highly bone metastatic), and DU145 (androgen-independent/moderate brain metastatic) cells by Western blotting.