APOB and atherosclerosis: PH is characterized by elevated plasma levels of cholesterol–specifically, LDL and apoB–which contribute to the development of atherosclerosis and associated ischemic events (Sampietro et al., 1997; Chironi et al., 2006; Real et al., 2010; Holven et al., 2014; Cortes et al., 2016; Collado et al., 2018a; Hansen et al., 2019).