When stratifying by clinical type of SSc (Figure 1), patients with lcSSc presented a median of 160 ng/ml (IQR 112.85–213.51 ng/ml) for Gal-1, and patients with dcSSc showed a median of 188.78 ng/ml (IQR 129.74–317.25 ng/ml) (p = 0.13). The gene discussed is LGALS1; the disease is systemic sclerosis.