CCL2 and Stroke: Atorvastatin reduced the IL-6, IL-8, and MCP-1 secretion in co-cultures of MSCs and human monocytes. When monocytes from stroke patients were co-cultured with MSCs in presence of atorvastatin (8–8000 nM), we found that IL-6, MCP-1, and IL-8 secretion was reduced at almost all atorvastatin doses (p < 0.05, Figure 3).