PLA2G7 and Parkinson disease: In another study, Seet et al. (2010) in the detection of plasma lipid and DNA oxidation products in 61 PD patients, found that compared with the control group, the plasma PLA2 and PAF-AH activities of PD patients were reduced, which led to an accumulation of esterified F2-isoprostanes in the lipids and participated in the onset and progression of PD.