BDNF and myeloid sarcoma: Their protective function is likely related to the secretion of antiapoptotic, anti-inflammatory, and neurotropic factors (through the activation of astroglial cells to secrete neurotrophins such as BDNF, glial cell-derived neurotrophic factor, and nerve growth factor),139 as well as the probable recruitment of local progenitor cells for subsequent differentiation into neurons and oligodendrocytes.139–141 These promising results encourage the use of MSCs in MS.