Interestingly, cells expressing MYB-Δ3 were rescued significantly from the induction of CD11b expression and apoptosis induced by AIB and HA (Fig. 4A, B) or related STLs (Supplementary Fig. 9), further supporting the notion that C/EBPβ is a relevant pro-leukemogenic cooperating factor of MYB in human AML cells. Here, ITGAM is linked to acute myeloid leukemia.