ADIPOQ and obesity due to melanocortin 4 receptor deficiency: Adiponectin promotes proliferation and wound repair of human bronchial epithelial cells152 and limits excessive lung inflammatory responses to invasive Aspergillosis in lean mice.153 Intuitively, an association between decreased adiponectin levels in obesity and immune cell hyperresponsiveness to influenza A has been suggested,154 highlighting the potential role of obesity-altered adipocytes.