MARCKS and leukemia: Bearing a remarkable physiological and pathological similarity to MARCKS, the lymphocyte-specific protein 1 harbors phosphorylation sites for serine/threonine kinases, in addition to actin-binding sites for interacting with F-actin, and regulates neutrophil chemotaxis during inflammation [133], and is also frequently overexpressed in a wide range of lymphomas and leukemias [122, 134, 135].