In concordance with our GSEA results, the percentage of neutrophils expressing LFA-1 was higher in the neutrophils of patients with AAV than in those of the disease controls and HCs (HC vs. AAV vs. GCA vs. TAK vs. PAN; 44% vs. 34% vs. 31% vs. 41% vs. 20%, P = 0.0006) (Fig. 3A-a). Here, ITGB2 is linked to polyarteritis nodosa.