INS and diabetes mellitus: Barr et al. [23] did not demonstrate a significant association with abnormal HOMA of insulin sensitivity (HOMA-%S) quintiles and all-cause mortality (quintile Hazard ratio 1.1, 95% CI: 0.8–1.7) on 8533 subjects aged > 35 years as part of the population-based Australian Diabetes, Obesity and Lifestyle study.