For example, within the context of prostate adenocarcinoma (TCGA-PRAD), mutations of FOXA1 that overlap with the fork head binding domain are much easier to predict than all FOXA1 point mutations taken together (22/31 FOXA1 mutants; AUC = 0.953 vs. AUC = 0.842; cvSig; \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$p_{Divg}$$\end{document}pDivg: 0.033). The gene discussed is FOXA1; the disease is prostate adenocarcinoma.