Murthy et al previously reported that in SLE patients isolated IgA anti-β2GPI positivity remained as an independent risk factor for AT but not VTE, after adjustment for other risk factors.42 Furthermore, we recently reported similar exclusive association of IgA anti-β2GPI domain1 antibodies.29 In our study IgA aPS/PT commonly co-occurred with IgG/M aPS/PT isotypes. The gene discussed is CD79A; the disease is systemic lupus erythematosus.