The RM effects were also studied in Poeciliopsis lucida hepatocellular carcinoma-derived PLHC-1 cell line (Fig. S4) in which expression of the erα and vtg biomarkers was induced at high concentrations by Mix14, Mix14NWL and Mix19NWL but not stimulated by the Mix19 or HM. This evidence concerns the gene CHCHD5 and hepatocellular carcinoma.