CD274 and lung carcinoma: In this study we found that PD-L1 expression in at least some lung cancer cases was associated with wild-type EGFR. Zhang M et al., performed a meta-analysis of over 11,000 lung cancer patients from 47 studies and concluded the unfavourable prognostic values of PD-L1 as well as the correlation between PD-L1 expression and EGFR wild-type status [36].