CAMK2G and Ventricular arrhythmia: Experimental use of CaMKII inhibition using small molecules and genetic approaches in animal models have been effective in preventing or reducing ventricular arrhythmias and pro-arrhythmic SR Ca2+ leak (Bezzerides et al., 2019; Chelu et al., 2009; Lebek et al., 2018; Neef et al., 2018).