Furthermore, TUNEL staining revealed that the proportion of TUNEL‐positive cells in xenografts of PC‐9‐derived LCSC tumour‐bearing mice was increased after anlotinib treatment in addition to the up‐regulated expression of Bax and cleaved caspase‐3 and the down‐regulated expression of Bcl‐2. The gene discussed is BCL2; the disease is neoplasm.