Additionally, diagnostic analysis results indicated that HPSE, IFI27, LGALS3BP, CRYM, HBD, COL6A3, LAMB2, and IFITM3 (AUC > 0.7, p < 0.001)30 had predictive validation value for pan‐cancer based on the data from GSE68086 and GSE89843 (Figure 5B, Figure S6B). The gene discussed is HPSE; the disease is cancer.