GSTM1 and anemia (phenotype): The key elements start with triage of a child with suspected severe anaemia, incorporating an assessment of severity (to determine the need for a transfusion), with further management guided initially by an assessment of Hb (or haematocrit if Hb is not possible) and fever status at the time a blood transfusion is ordered from the blood transfusion service, in order to determine whether to request a higher volume of blood (30 ml/kg WB or 15 ml/kg RCC), or standard volume (20 ml/kg WB or 10 ml/kg RCC) if fever is present.