TSPAN5 and cancer: Further investigation of Kaplan–Meier Plotter dataset (Pan‐cancer RNA‐seq) demonstrated that high expression of Tspan5 was significantly correlated with poor overall survival of all HCC patients (P = 0.0141), stratified patients with pathological grade 3 (P = 0.0106) and high mutation burden (P = 0.0042) (Fig. 1D).