The expression of ADAM10, Notch1, Notch2, Notch3, Notch4, Hey1, vimentin and N‐cadherin at the transcript level was significantly upregulated, whereas transcripts of E‐cadherin significantly decreased in tumour tissues versus in normal liver tissues of HCC (Fig. 6A). The gene discussed is NOTCH4; the disease is hepatocellular carcinoma.