TSPAN5 and neoplasm: F‐actin staining of tumour cells with Rhodamine‐phalloidin revealed that upregulation of Tspan5 significantly increased the expression of F‐actin and propelled actin cytoskeleton rearrangement in both MHCC97L‐Tspan5 and BEL7402‐Tspan5 cells as compared with that of the control cells.