CD1D and fungal infectious disease: To determine the role of the iNKT cells in the immunity against P. brasiliensis, we tested the ability of naïve splenocytes from CD1d−/− mouse, deficient in diverse CD1d-restricted cells, or Jα18−/− mouse strain, which lacks only the CD1d-restrict iNKT cell subset, to respond to fungal infection [13, 23].