Univariate Cox regression revealed prognostic values of CD86 expression, age, tumor grade, as well as molecular subtypes including IDH mutation status, X1p/19q codeletion, and MGMT methylation (Figure 7A); whereas, multivariate Cox regression showed independent prognostic roles of CD86 expression, age, tumor grade, and IDH mutation status in overall survival of LGG (Figure 7B). This evidence concerns the gene CD86 and neoplasm.