The four most enriched biological KEGG pathway were (1) pathways in cancer (5.49E-36); (2) TNF signaling pathway (2.45E-26); and (3) proteoglycans in cancer (1.86E-21), PI3K-Akt signaling pathway (6.99E-21), containing 101, 46, 56, and 74 genes related to pathways enrichment analysis, respectively, and other highly enriched pathways including FoxO signaling pathway, HIF-1 signaling pathway, MAPK signaling pathway, prolactin signaling pathway, osteoclast differentiation, apoptosis, chemokine signaling pathway, and Toll-like receptor signaling pathway. This evidence concerns the gene TNF and cancer.