Pegylated forms of IFNα and IFNβ have been used in the setting of Hepatitis B and C (Pegylated Alfa-2a/Pegasys, Genentench Inc.)and in Multiple Sclerosis (Pegylated interferon beta-1a/Plegridy, Biogen Canada) [67–69]. The gene discussed is IFNB1; the disease is hepatitis B virus infection.