Scholars Wu and Huang discussed TAP and other serological biomarkers such as carcinoembryonic antigen (CEA), antigen 125 (CA125) sugar, and sugar antigen 19-9 (CA19-9) relationship, and its clinical application in patients with colorectal cancer (CRC) results showed that the TAP detection in CRC patients with high sensitivity and specificity of clinical monitoring in the process of CRC patients with chemotherapy can be used as a new independent index [17]. This evidence concerns the gene CEACAM5 and colorectal carcinoma.