INS and diabetes mellitus: Puerarin exerts positive hypoglycemic and hypolipidemic roles on mice with diabetes induced by streptozotocin by increasing insulin expression and maintaining metabolic homoeostasis, and it exerts a regulatory effect on lipid accumulation in oleic acid-treated HepG2 cells by decreasing lipogenesis and increasing antioxidant activity, both indicating that puerarin extract has therapeutic benefits in the treatment of glucose- and lipid-related metabolic disorders [65, 66].