We also evaluated the association between KDM5C expression and several inhibitory (e.g., CD160, CD96, CSF1R, CTLA-4, TIM-3, IDO1, IL10, LAG3, PD-1, PD-L1, PD-L2, TFGB1, TGFBR1, TIGIT, VEGFA) and stimulatory (e.g., CD27, CD28, CD40, CD40LG, CD70, CD80, CD86, CXCL12, CXCR4, ICOS, ICOSLG, MICA, MICB, TNFRSF14, TNFRSF17, TNFRSF18, TNFRSF4, TNFRSF9, TNFSF9, TNFSF13) immune checkpoints expression in various cancers. The gene discussed is ICOS; the disease is cancer.