Both OVA and hTregitope 084/289-treated Tregs (OVA-hTR 084/289-Treg) and OVA and hTregitope 167/289-treated Tregs (OVA-hTR 167/289-Treg) improved airway inflammation when transferred to OVA-allergic mice and were significantly more suppressive than OVA and vehicle-control-treated Tregs (OVA-Control-Tregs) as shown by significant decreases in OVA-specific IgE and lung inflammation scores (Figures 6A–C). This replicates the data obtained, showing that Ragweed-Tregitope-Tregs improve ragweed-driven lung inflammation more effectively than Ragweed-vehicle control-treated Tregs (Figures 5B, C). The gene discussed is IGHE; the disease is inflammation.