In order to determine the therapeutic efficacy of the liposomal BDNF -AT (AT-LIPO), we next examined both tyrosine hydroxylase (TH) and BDNF protein expression within the striatum and substantia nigra in an established 6-OHDA rat model of PD (Rabie et al., 2018). The gene discussed is BDNF; the disease is Parkinson disease.