AMBRA1 and neoplasm: Remarkably, the kinetics of tumor growth was dramatically reduced upon FAKi administration in sBPA−/− mice (Fig. 5l and Supplementary Fig. 7e–g), as also demonstrated by reduced tumor weight at the time of collection (Fig. 5m), underlining the key role of the FAK1 signaling axis in sustaining Ambra1-deficient tumors.