AMBRA1 and melanoma: On the other hand, the re-expression of the HA-FAK1.miResAA mutant resulted in a higher migratory capacity than that induced by WT FAK (HA-FAK1.miRes) (Supplementary Fig. 7d), supporting the relevance of the AMBRA1-FAK1 interaction in determining the invasive ability of melanoma cells in our settings.