DST and melanoma: To further unravel this aspect, we performed wound-healing and transwell migration assays both ex vivo, i.e., in melanoma cells isolated from BPA+/+ and BPA−/− mice (Bdmc+/+ and Bdmc−/−, respectively) (Supplementary Fig. 4b, c), and in vitro, i.e., in human melanoma cell lines upon siAMBRA1-mediated knockdown (Fig. 3g, h and Supplementary Fig. 4d–g).