Based on single-cell expression levels of genes commonly used as markers for immunohistochemistry-based NSCLC classification, namely NAPSA, TTF-1 (NKX2-1) for lung adenocarcinoma (LUAD), and TP63, CK5 (KRT5) for lung squamous carcinoma (LUSC), subtype classifications aligned well with the histopathological classifications (Fig. S2). This evidence concerns the gene TP63 and non-small cell lung carcinoma.