Similarly, all six human HCC cell lines (HepG2, MHCC-97H, MHCC-97L, SMMC7721, Hep3B, and Huh7) had higher SOX2 (Figure 1B) and CCAT1 (Figure 1C) expression than the normal human liver cell line LO2. This evidence concerns the gene SOX2 and hepatocellular carcinoma.