Another example is DDX3, which normally inhibits cell growth by activating CDKN1A (also called p21WAF1 or CIP1) but is down-regulated in hepatic cancers [25] and whose translocation from the nucleus to the cytoplasm has been implicated in cutaneous squamous cell carcinoma [26, 27]. This evidence concerns the gene CDKN1A and cutaneous squamous cell carcinoma.