RNPC3 and viral infectious disease: Of note, propagation of EBOV-trVLP in Huh7-4PX cells is considerably less efficient than that of infectious EBOV in Huh7 cells, suggesting that an artificially fixed stoichiometry of RNP components in Huh7-4PX cells may be still less optimal for virion production than the dynamically changing ratio of each RNP component during the natural virus infection.