TP53 and cancer: The following transcription factors that appear to be involved in the development and progression of cancer have been identified as being present within the repeat sequence: GR-alpha, GR-beta [32], EBF [33], C/EBPbeta [34], NF-1 [35], FOXP3 [36], Pax-5 [37, 38], p53 [39], STAT4 [40] and TFII-I [41].