Recently, we reviewed the top 10 frequently mutated genes (e.g., TP53, RB1, PTEN, DLG2, MYC, ATRX, NF1, CCNE1, CDKN2A, and PIK3CA) and some tumor‐specific CNAs (e.g., MYC, CCNE1, VEGFA, BRCA1/2, TP53, RB1, CDKN2A/2B) in OS tissues identified by NGS technology.32 This evidence concerns the gene CDKN2A and neoplasm.