CD274 and neoplasm: During the examination of programmed cell death‐1 ligand (PD‐L1) as a key element in the tumor microenvironment and a target of immunotherapy, Toyokawa et al.13, 15reported that there is no association between PD‐L1 expression and the presence of STAS; in addition, no report has shown an association between STAS and PD‐L1 to date.