CD34 and spindle cell lipoma: Immunohistochemically, spindle cell lipoma is characterized by the diffuse expression of CD34.[3] Recently, CD10 expression[4] and loss of nuclear expression of retinoblastoma protein have been reported.[5] Spindle cell lipoma often occurs as an asymptomatic, slow-growing subcutaneous tumor in the upper back, back neck, and shoulders of elderly men,[1] including unusual locations such as the leg, perineum, groin, buttocks, and foot fingers, etc.[6] However, reports of spindle cell lipoma in the hypopharynx are extremely rare.