SLE had been diagnosed 5 years previously, when she presented with 6 of the 11 ACR criteria[29] (arthritis, malar rash, oral ulcers, direct Coombs’ positive autoimmune hemolytic anemia, high titers of ANA (1:1280) and elevated anti-dsDNA antibody titers). This evidence concerns the gene BTG3 and systemic lupus erythematosus.