CD44 and neoplasm: Interestingly, p‐Src levels are also reduced upon treatment with Porc inhibitor (Fig 8C), possibly reflecting a role of the Wnt target gene CD44 in promoting Src activation and LATS1/2 inhibition in crypts, similar to its function in other cell and tumour types (Bourguignon et al,2001; Li et al,2001; Xu et al,2010; Nam et al,2015; Pastushenko et al,2021).