This is of great importance given that mutations in Cdh13 have been associated with a vast number of neuropsychiatric disorders including ADHD (Rivero et al., 2013), depression (Edwards et al., 2012), schizophrenia (Otsuka et al., 2015; Børglum et al., 2014), and bipolar disorder (Cho et al., 2015b). This evidence concerns the gene CDH13 and depressive symptom measurement.