As previously reported, NEDD4‐2 bound to ion channels (I Na and I Kr), resulted in ubiquitination and degradation, and thus its isoform NEDD4‐2 C2‐induced electrophysiological impairment and triggered both cardiac conduction alterations and pro‐arrhythmic changes in post‐acute myocardial infarctions.30 The gene discussed is NEDD4L; the disease is myocardial infarction.