The suppression of ZASP/cypher protein induced by LDB3 pathogenic mutation was associated with DCM, left ventricular noncompaction (LVNC), arrhythmogenic cardiomyopathy (ACM) (Lopez‐Ayala et al., 2015), HCM (Fratev et al., 2014), heart failure (HF), and SCD (Vatta et al., 2003). This evidence concerns the gene LDB3 and heart failure.