MMP‐2/‐9 and Cyclin D1 are targets of Tcf/β‐catenin genes and were found to be upregulated in endometrial epithelial or stromal cells of EM,107 MMPs are responsible for regulating migration, invasion, and angiogenesis by balancing growth factors and cytokines, and high expression of MMPs in EM favors lesions.217. The gene discussed is MMP2; the disease is erythema multiforme.