STAT3 and acute myeloid leukemia: For G-CSF-induced pY-STAT3 (Fig. 3a), patients whose AML cells had a ∆MFI ≤ 1.5 had an inferior EFS (n = 24; 5-year EFS 29.2 ± 18.6%) compared to patients whose AML cells had a ∆MFI > 1.5 (n = 87; 5-year EFS 56.4 ± 10.8%; p = 0.044).