Activation of the EMT migratory program has been associated with metastasis of several cancers including medulloblastoma, leading us to investigate the expression of transcription factors (SNAI2 and TWIST1) that are expected to initiate the EMT program.33 The publicly available Pfister34 and Roth35 patient datasets revealed lower SNAI2 expression in medulloblastoma patient samples compared to the normal cerebellum, whereas TWIST1 expression was significantly increased in medulloblastoma samples. Here, TWIST1 is linked to cancer.